HitPredict

Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: PP4R1 (Q8TF05)
Serine/threonine-protein phosphatase 4 regulatory subunit 1
Gene: PPP4R1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HEAT~HEAT, HEAT~HEAT_2
Common GO terms	GO:0005737 - cytoplasm GO:0019888 - protein phosphatase regulator activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 950
+	Hs
		672452 2AAB_HUMAN (9-589): 7.23e-158: 466: 86.40		PP4R1_HUMAN (1-950): 0: 1060: 100.00
+	Hs
		672002 2AAA_HUMAN (1-589): 2.84e-166: 487: 100.00		2AAB_HUMAN (67-715): 6e-10: 64.9: 13.40
+	Hs
		672379 2AAB_HUMAN (9-589): 7.23e-158: 466: 86.40		2AAB_HUMAN (67-715): 6e-10: 64.9: 13.40
+	Hs
		1268224 GCN1_HUMAN (28-589): 5.37e-25: 112: 16.01		SCYL1_HUMAN (62-500): 5.67e-96: 322: 15.00
+	Sp
		1358061 2AAA_SCHPO (5-393): 1.82e-31: 131: 21.41		2AAA_SCHPO (4-385): 1.52e-29: 126: 13.37