Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: M3K3 (Q99759)
Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)
Gene: MAP3K3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 14743216
Identification Methods tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT~Pkinase, HEAT_2~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0035556 - intracellular signal transduction
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 589
Hs

1 626
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ At

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Last updated: 15 Jul 2024