Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: P2R3B (Q9Y5P8)
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (PP2A subunit B isoform PR48) (Protein phosphatase 2A 48 kDa regulatory subunit)
Gene: PPP2R3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 26496610, 28330616, 18782753, 12370081, 33961781
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~HEAT_2
Common GO terms GO:0000159 - protein phosphatase type 2A complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019888 - protein phosphatase regulator activity
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 589
Hs

1 575
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024