HitPredict

Interactor 1: 2AAB (P30154)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta)
Gene: PPP2R1B

Interactor 2: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 601 Hs			1 635
+	Hs
		672026 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		KSYK_HUMAN (1-635): 0: 589: 100.00
+	Hs
		507873 2AAB_HUMAN (1-601): 8.13e-170: 497: 100.00		FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24
+	Hs
		337994 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		337995 2AAB_HUMAN (1-601): 8.13e-170: 497: 100.00		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		383637 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		ERBB2_HUMAN (375-619): 1.47e-52: 197: 42.34
+	Hs
		672042 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		BMX_HUMAN (15-193): 8.37e-12: 70.3: 22.82
+	Hs
		268579 SF3B1_HUMAN (147-580): 4.07e-18: 90.6: 13.84		YES_HUMAN (4-203): 1.25e-68: 234: 20.80
+	Hs
		338800 TNPO1_HUMAN (36-489): 1.07e-13: 76.4: 15.34		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		338782 GCN1_HUMAN (20-600): 6.38e-12: 71: 14.37		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		155507 TNPO2_HUMAN (37-386): 1.53e-10: 66.4: 15.42		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		383912 TNPO1_HUMAN (36-489): 1.07e-13: 76.4: 15.34		ERBB2_HUMAN (375-619): 1.47e-52: 197: 42.34