HitPredict

Interactor 1: 2AAB (P30154)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta)
Gene: PPP2R1B

Interactor 2: 2ABA (P63151)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)
Gene: PPP2R2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.737

The method score is based on:

Property Details
Experiments 26496610, 28330616, 1328247, 19156129, 12370081, 17540176
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000159 - protein phosphatase type 2A complex
GO:0005829 - cytosol
GO:0019888 - protein phosphatase regulator activity
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 601
Hs

1 447
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Ca

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024