Interactor 1: CD6 (P30203)
T-cell differentiation antigen CD6 (T12) (TP120) (CD antigen CD6) [Cleaved into: Soluble CD6]
Gene: CD6

Interactor 2: CD166 (Q13740)
CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
Gene: ALCAM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.708

The method score is based on:

Property Details
Experiments 7543097, 33961781, 26146185, 24945728
Identification Methods pull down, affinity chromatography technology, mass spectrometry studies of complexes, light scattering, molecular sieving, competition binding, anti tag coimmunoprecipitation, enzyme linked immunosorbent assay
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001772 - immunological synapse
GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 668
Hs

1 583
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024