Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: APC16 (Q96DE5)
Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16)
Gene: ANAPC16

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 25490258, 33961781, 35271311, 32152539, 32076268, 22193957, 21043528, 20360068
Identification Methods affinity chromatography technology, x-ray crystallography, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC16~TPR_1, ANAPC16~TPR_8
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0016567 - protein ubiquitination
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 824
Hs

1 110
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024