HitPredict

Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: APC13 (Q9BS18)
Anaphase-promoting complex subunit 13 (APC13) (Cyclosome subunit 13)
Gene: ANAPC13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.916

The method score is based on:

Property Details
Experiments 32076268, 21043528, 28514442, 33961781, 20360068
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Apc13p~TPR_1, Apc13p~TPR_8
Common GO terms GO:0005680 - anaphase-promoting complex
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
GO:0051301 - cell division
GO:0051445 - regulation of meiotic cell cycle
and 1 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 824
Hs

1 74
+ Hs
+ Hs
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024