Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: ANC2 (Q9UJX6)
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)
Gene: ANAPC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 12956947, 10922056, 25306918, 26811472, 27114510, 32152539, 32076268, 35271311, 14657031, 22193957, 16364912, 21043528, 22280307, 16648845, 21768287, 17443186, 20360068
Identification Methods affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle
GO:0007346 - regulation of mitotic cell cycle
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 824
Hs

1 822
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+ Dm
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+ Sc
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Last updated: 15 Jul 2024