Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: APC10 (Q9UM13)
Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10)
Gene: ANAPC10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 12956947, 26496610, 32076268, 10922056, 35271311, 14657031, 22193957, 16364912, 22792066, 21043528, 10498862
Identification Methods affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ANAPC10~TPR_1, ANAPC10~TPR_8
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0031145 - anaphase-promoting complex-dependent catabolic process
and 3 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 824
Hs

1 185
+ Xl
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Sp
+ Sc
+ At
+ At
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024