HitPredict

Interactor 1: CCND2 (P30279)
G1/S-specific cyclin-D2
Gene: CCND2

Interactor 2: CDN1A (P38936)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
Gene: CDKN1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 25416956, 26186194, 16189514, 28514442, 9823309, 30217970, 27107012, 10022865, 11971966, 32296183, 33961781, 8756624, 15169570, 16765349, 23443559, 31515488, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, validated two hybrid, barcode fusion genetics two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach, two hybrid prey pooling approach, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Cyclin_N
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001934 - positive regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 289
Hs

1 164
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Last updated: 15 Jul 2024