Interactor 1: CCND3 (P30281)
G1/S-specific cyclin-D3
Gene: CCND3
Interactor 2: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.981 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 16189514, 28514442, 33961781, 34591612, 10597239, 9716181, 8978686, 16782892, 23718855, 11360184, 10342870 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, two hybrid pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDI~Cyclin_N |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0001934 - positive regulation of protein phosphorylation GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
