HitPredict

Interactor 1: CCND3 (P30281)
G1/S-specific cyclin-D3
Gene: CCND3

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0007165 - signal transduction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 292 Hs			1 2442
+	Hs
		622500 CCND1_HUMAN (2-292): 1.65e-100: 298: 51.86		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		590210 CCNA2_HUMAN (1-283): 1.9e-87: 269: 25.61		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		624599 CCNE1_HUMAN (14-208): 1.34e-15: 78.2: 29.13		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		622441 CCND1_HUMAN (2-292): 1.65e-100: 298: 51.86		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		943778 CCNA1_HUMAN (4-283): 4.44e-93: 284: 25.89		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		538531 CCNB1_HUMAN (10-285): 8.22e-89: 272: 23.02		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		590170 CCNA2_HUMAN (1-283): 1.9e-87: 269: 25.61		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		624580 CCNE1_HUMAN (14-208): 1.34e-15: 78.2: 29.13		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		590236 CCNA2_HUMAN (1-283): 1.9e-87: 269: 25.61		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83