HitPredict

Interactor 1: MIP (P30301)
Lens fiber major intrinsic protein (Aquaporin-0) (MIP26) (MP26)
Gene: MIP

Interactor 2: AQP6 (Q13520)
Aquaporin-6 (AQP-6) (Aquaporin-2-like) (Kidney-specific aquaporin) (hKID)
Gene: AQP6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	MIP~MIP
Common GO terms	GO:0005886 - plasma membrane GO:0006833 - water transport GO:0015250 - water channel activity GO:0016324 - apical plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 263 Hs			1 282
+	Hs
		670331 AQP1_HUMAN (3-261): 6.43e-87: 261: 43.99		AQP6_HUMAN (1-282): 1.21e-100: 297: 100.00
+	Hs
		876218 AQP4_HUMAN (6-260): 2.55e-86: 261: 42.48		AQP4_HUMAN (6-259): 2.39e-95: 285: 38.93
+	Hs
		670313 AQP1_HUMAN (3-261): 6.43e-87: 261: 43.99		AQP1_HUMAN (14-253): 6.75e-91: 272: 42.97
+	At
		794929 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP22_ARATH (2-255): 4.73e-92: 275: 30.91
+	At
		955415 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP27_ARATH (2-242): 2.77e-91: 273: 32.81
+	At
		1107212 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP28_ARATH (2-248): 9.58e-91: 272: 34.73
+	At
		902174 PIP11_ARATH (2-225): 2.07e-83: 252: 33.76		PIP27_ARATH (2-242): 2.77e-91: 273: 32.81
+	At
		794727 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP21_ARATH (2-238): 3.04e-90: 271: 32.56
+	At
		794924 PIP22_ARATH (3-229): 5.23e-83: 251: 31.71		PIP27_ARATH (2-242): 2.77e-91: 273: 32.81
+	At
		794704 PIP11_ARATH (2-225): 2.07e-83: 252: 33.76		PIP21_ARATH (2-238): 3.04e-90: 271: 32.56
+	At
		673355 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP23_ARATH (2-238): 1.52e-89: 269: 31.78
+	At
		794680 PIP22_ARATH (3-229): 5.23e-83: 251: 31.71		PIP21_ARATH (2-238): 3.04e-90: 271: 32.56
+	At
		988191 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP12_ARATH (2-237): 2.14e-89: 269: 33.87
+	At
		673351 PIP11_ARATH (2-225): 2.07e-83: 252: 33.76		PIP23_ARATH (2-238): 1.52e-89: 269: 31.78
+	At
		902175 PIP11_ARATH (2-225): 2.07e-83: 252: 33.76		PIP12_ARATH (2-237): 2.14e-89: 269: 33.87
+	At
		1107211 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP25_ARATH (2-242): 5.22e-89: 267: 33.21
+	At
		794925 PIP22_ARATH (3-229): 5.23e-83: 251: 31.71		PIP12_ARATH (2-237): 2.14e-89: 269: 33.87
+	At
		902181 PIP11_ARATH (2-225): 2.07e-83: 252: 33.76		PIP25_ARATH (2-242): 5.22e-89: 267: 33.21
+	At
		996284 PIP14_ARATH (2-225): 1.32e-83: 253: 33.33		PIP13_ARATH (2-237): 1.04e-83: 254: 34.26
+	At
		794926 PIP22_ARATH (3-229): 5.23e-83: 251: 31.71		PIP13_ARATH (2-237): 1.04e-83: 254: 34.26