HitPredict

Interactor 1: MPIP1 (P30304)
M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A)
Gene: CDC25A

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27432908
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 524 Hs			1 248
+	Hs
		673381 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		673382 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Rn
		823139 MPIP1_RAT (1-524): 0: 673: 84.09		1433E_RAT (2-246): 4.41e-146: 410: 60.41
+	Hs
		646655 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		673365 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		673380 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		673390 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		673453 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Rn
		823141 MPIP2_RAT (30-522): 0: 564: 41.51		1433E_RAT (2-246): 4.41e-146: 410: 60.41
+	Hs
		673463 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		673464 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Xl
		223343 MPIP2_XENLA (34-524): 6.68e-172: 500: 37.24		O57468_XENLA (2-246): 5.73e-145: 407: 60.00
+	Hs
		673546 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		646656 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Mm
		673543 MPIP2_MOUSE (30-522): 0: 565: 42.75		1433B_MOUSE (1-239): 3.73e-99: 290: 68.62
+	Hs
		673452 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		673462 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		673471 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		646657 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		673545 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62