HitPredict

Interactor 1: MPIP1 (P30304)
M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A)
Gene: CDC25A

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	27432908, 28330616, 28675297
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 524 Hs			1 247
+	Hs
		673381 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		673390 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Rn
		823139 MPIP1_RAT (1-524): 0: 673: 84.09		1433E_RAT (1-244): 2.02e-141: 398: 63.53
+	Hs
		673365 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		673382 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646655 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		673366 MPIP1_HUMAN (1-524): 0: 723: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Rn
		823141 MPIP2_RAT (30-522): 0: 564: 41.51		1433E_RAT (1-244): 2.02e-141: 398: 63.53
+	Hs
		673463 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		673462 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		673471 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Xl
		223343 MPIP2_XENLA (34-524): 6.68e-172: 500: 37.24		O57468_XENLA (1-244): 4.25e-141: 397: 63.12
+	Mm
		673543 MPIP2_MOUSE (30-522): 0: 565: 42.75		1433B_MOUSE (2-247): 8.57e-109: 315: 75.81
+	Hs
		673452 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		673464 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646656 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		673453 MPIP2_HUMAN (32-522): 0: 544: 43.02		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		673545 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		646657 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		673546 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16