HitPredict

Interactor 1: MPIP1 (P30304)
M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A)
Gene: CDC25A

Interactor 2: CCNI (Q14094)
Cyclin-I
Gene: CCNI

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 524 Hs			1 377
+	Hs
		673386 MPIP1_HUMAN (1-524): 0: 723: 100.00		CCNA1_HUMAN (9-275): 1.52e-84: 266: 15.67
+	Hs
		538480 MPIP1_HUMAN (1-524): 0: 723: 100.00		CCNB1_HUMAN (5-272): 1.51e-81: 257: 18.52
+	Hs
		590131 MPIP1_HUMAN (1-524): 0: 723: 100.00		CCNA2_HUMAN (10-271): 4.71e-74: 238: 17.49
+	Hs
		624548 MPIP1_HUMAN (1-524): 0: 723: 100.00		CCNE1_HUMAN (3-298): 7.23e-67: 218: 19.06
+	Hs
		538481 MPIP2_HUMAN (32-522): 0: 544: 43.02		CCNB1_HUMAN (5-272): 1.51e-81: 257: 18.52
+	Hs
		590132 MPIP2_HUMAN (32-522): 0: 544: 43.02		CCNA2_HUMAN (10-271): 4.71e-74: 238: 17.49
+	Xl
		673650 MPIP3_XENLA (34-521): 3.99e-166: 484: 36.88		Q6IR86_XENLA (5-280): 8.2e-76: 241: 19.78
+	Hs
		538482 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		CCNB1_HUMAN (5-272): 1.51e-81: 257: 18.52
+	Hs
		303831 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		CCNB2_HUMAN (5-287): 4e-77: 244: 15.44
+	Hs
		624549 MPIP3_HUMAN (31-523): 1.2e-156: 456: 34.46		CCNE1_HUMAN (3-298): 7.23e-67: 218: 19.06
+	Xl
		193810 MPIP3_XENLA (34-521): 3.99e-166: 484: 36.88		CCNE3_XENLA (25-208): 3.63e-54: 185: 27.03
+	Sc
		620002 MPIP_YEAST (357-509): 7.06e-55: 195: 35.37		CG23_YEAST (14-272): 1.12e-67: 221: 18.15
+	Sc
		620005 MPIP_YEAST (357-509): 7.06e-55: 195: 35.37		CGS5_YEAST (23-228): 1.39e-45: 163: 22.33