HitPredict

Interactor 1: MPIP2 (P30305)
M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)
Gene: CDC25B

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.758

Property	Details
Experiments	10713667, 33961781, 30468767, 26496610, 27432908, 7644510, 21558810, 28514442, 12871587, 15173315, 16672277
Identification Methods	pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 580 Hs			1 246
+	Rn
		823141 MPIP2_RAT (1-580): 0: 830: 79.66		1433E_RAT (3-243): 4.39e-144: 405: 65.43
+	Mm
		673543 MPIP2_MOUSE (1-580): 0: 833: 80.90		1433B_MOUSE (1-246): 5.56e-141: 396: 98.78
+	Hs
		673463 MPIP2_HUMAN (1-580): 0: 823: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		673464 MPIP2_HUMAN (1-580): 0: 823: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		646656 MPIP2_HUMAN (1-580): 0: 823: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		673462 MPIP2_HUMAN (1-580): 0: 823: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		673471 MPIP2_HUMAN (1-580): 0: 823: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		673453 MPIP2_HUMAN (1-580): 0: 823: 100.00		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		673381 MPIP1_HUMAN (46-578): 0: 636: 44.73		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		673365 MPIP1_HUMAN (46-578): 0: 636: 44.73		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		673382 MPIP1_HUMAN (46-578): 0: 636: 44.73		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Rn
		823139 MPIP1_RAT (45-578): 0: 618: 42.59		1433E_RAT (3-243): 4.39e-144: 405: 65.43
+	Hs
		646655 MPIP1_HUMAN (46-578): 0: 636: 44.73		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		673380 MPIP1_HUMAN (46-578): 0: 636: 44.73		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		673390 MPIP1_HUMAN (46-578): 0: 636: 44.73		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Xl
		223343 MPIP2_XENLA (49-577): 0: 536: 35.53		O57468_XENLA (4-243): 2.71e-143: 402: 66.12
+	Hs
		673366 MPIP1_HUMAN (46-578): 0: 636: 44.73		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		673545 MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		646657 MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		673546 MPIP3_HUMAN (160-577): 2.99e-146: 432: 35.10		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62