HitPredict

Interactor 1: MPIP3 (P30307)
M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C)
Gene: CDC25C

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	28094252, 10330186, 35271311, 36931259, 27880917, 28675297, 10681541, 15791647, 19331823
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 473 Hs			1 255
+	Xl
		223343 MPIP2_XENLA (1-469): 0: 569: 42.99		O57468_XENLA (1-255): 1.7e-152: 426: 96.47
+	Rn
		89019 D4ADT2_RAT (1-473): 0: 546: 60.55		1433E_RAT (1-255): 4.87e-154: 430: 100.00
+	Mm
		823143 MPIP3_MOUSE (1-473): 0: 541: 59.24		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Rn
		823141 MPIP2_RAT (112-468): 2.07e-143: 424: 38.80		1433E_RAT (1-255): 4.87e-154: 430: 100.00
+	Hs
		673381 MPIP1_HUMAN (95-469): 2.75e-141: 417: 37.95		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		673463 MPIP2_HUMAN (121-468): 2.83e-140: 416: 40.11		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Rn
		823139 MPIP1_RAT (95-469): 5.83e-131: 391: 36.83		1433E_RAT (1-255): 4.87e-154: 430: 100.00
+	Sp
		416121 MPIP_SCHPO (133-442): 7.65e-86: 276: 26.52		RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77
+	Sp
		416122 MPIP_SCHPO (133-442): 7.65e-86: 276: 26.52		RAD25_SCHPO (2-236): 1.03e-134: 382: 74.89