HitPredict

Interactor 1: MPIP3 (P30307)
M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C)
Gene: CDC25C

Interactor 2: FHL1 (Q13642)
Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1)
Gene: FHL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	28094252, 35142956
Identification Methods	two hybrid, affinity chromatography technology, unspecified method, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 473 Hs			1 323
+	Hs
		673579 MPIP3_HUMAN (1-473): 0: 661: 100.00		FHL3_HUMAN (3-92): 3.86e-17: 81.9: 33.70
+	Hs
		673580 MPIP3_HUMAN (1-473): 0: 661: 100.00		FHL2_HUMAN (3-92): 4.15e-15: 76.2: 34.78
+	Hs
		673401 MPIP1_HUMAN (95-469): 2.75e-141: 417: 37.95		FHL1_HUMAN (1-323): 7.74e-90: 272: 100.00
+	Hs
		673478 MPIP2_HUMAN (121-468): 2.83e-140: 416: 40.11		FHL1_HUMAN (1-323): 7.74e-90: 272: 100.00
+	Dm
		594011 MPIP_DROME (69-472): 2.26e-106: 326: 28.86		Q9VVB5_DROME (155-242): 1.06e-09: 61.1: 23.71