Interactor 1: MPIP3 (P30307)
M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C)
Gene: CDC25C

Interactor 2: PLK3 (Q9H4B4)
Serine/threonine-protein kinase PLK3 (EC 2.7.11.21) (Cytokine-inducible serine/threonine-protein kinase) (FGF-inducible kinase) (Polo-like kinase 3) (PLK-3) (Proliferation-related kinase)
Gene: PLK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 14968113, 10557092
Identification Methods affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Rhodanese
Common GO terms GO:0000086 - G2/M transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 473
Hs

1 646
+ Hs
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024