Interactor 1: PPIF (P30405)
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Mitochondrial cyclophilin) (CyP-M) (Rotamase F)
Gene: PPIF

Interactor 2: PARL (Q9H300)
Presenilin-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]
Gene: PARL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 31617661
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0090201 - negative regulation of release of cytochrome c from mitochondria
GO:2001243 - negative regulation of intrinsic apoptotic signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 207
Hs

1 379
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024