Interactor 1: CED4 (P30429)
Cell death protein 4
Gene: ced-4
Interactor 2: CED9 (P41958)
Apoptosis regulator ced-9 (Cell death protein 9)
Gene: ced-9
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.90 | 0.938 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9027312, 9261161, 9027313, 9837929, 14555965, 16735440, 9024666, 9651369, 9721101, 9094313, 9645478, 9210374, 10403845, 11027303, 19855391, 16208361, 10846174, 10101135 |
| Identification Methods | affinity chromatography technology, two hybrid, x-ray crystallography, enzymatic study, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~CARD, Bcl-2~NB-ARC |
| Common GO terms | GO:0005739 - mitochondrion GO:0006915 - apoptotic process GO:0016020 - membrane GO:0030042 - actin filament depolymerization GO:0043065 - positive regulation of apoptotic process and 6 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
