Interactor 1: CED4 (P30429)
Cell death protein 4
Gene: ced-4
Interactor 2: CED3 (P42573)
Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13]
Gene: ced-3
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.90 | 0.933 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9027312, 9261161, 16938876, 9109415, 9651369, 9721101, 20434985, 11779177, 9285582, 9210374, 10101135 |
| Identification Methods | affinity chromatography technology, enzymatic study, pull down, anti tag coimmunoprecipitation, far western blotting, two hybrid, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD, CARD~NB-ARC |
| Common GO terms | GO:0005739 - mitochondrion GO:0006915 - apoptotic process GO:0006919 - activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0008303 - caspase complex GO:0008656 - cysteine-type endopeptidase activator activity involved in apoptotic process and 15 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
