HitPredict

Interactor 1: HLAF (P30511)
HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene: HLA-F

Interactor 2: KI3S1 (Q14943)
Killer cell immunoglobulin-like receptor 3DS1 (Natural killer-associated transcript 10) (NKAT-10)
Gene: KIR3DS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.802

Property	Details
Experiments	27649529, 27455421
Identification Methods	surface plasmon resonance, affinity technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	GO:0005886 - plasma membrane GO:0006955 - immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 346 Hs			1 382
+	Hs
		1060406 Q95J06_HUMAN (1-345): 6.76e-175: 491: 80.87		KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00
+	Hs
		382420 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00
+	Hs
		1060403 Q5SUL5_HUMAN (1-345): 2.11e-167: 472: 79.71		KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00
+	Hs
		382341 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		KI3L2_HUMAN (1-368): 6.34e-90: 279: 84.51
+	Hs
		798244 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		KI3L2_HUMAN (1-368): 6.34e-90: 279: 84.51
+	Hs
		47499 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		A0A8I5QEB2_HUMAN (1-368): 2.83e-83: 261: 70.65
+	Hs
		1245576 Q95J06_HUMAN (1-345): 6.76e-175: 491: 80.87		LIRB1_HUMAN (21-344): 4.61e-57: 198: 35.53
+	Hs
		382280 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		FGFR1_HUMAN (3-369): 3.89e-60: 209: 14.18
+	Hs
		382306 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		FGFR2_HUMAN (2-379): 8.05e-60: 208: 13.78
+	Hs
		1232786 Q95J06_HUMAN (1-345): 6.76e-175: 491: 80.87		LIRB2_HUMAN (1-341): 2.59e-55: 193: 35.53
+	Hs
		382485 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		LIRB1_HUMAN (21-344): 4.61e-57: 198: 35.53
+	Hs
		1130838 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		LIRB1_HUMAN (21-344): 4.61e-57: 198: 35.53
+	Hs
		382478 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		LIRB2_HUMAN (1-341): 2.59e-55: 193: 35.53
+	Hs
		1130837 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		LIRB2_HUMAN (1-341): 2.59e-55: 193: 35.53
+	Hs
		798280 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		KI2S4_HUMAN (1-253): 2.61e-43: 154: 34.88
+	Hs
		382484 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		LIRB4_HUMAN (21-137): 3.84e-21: 96.3: 34.43
+	Hs
		798195 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		KI2L3_HUMAN (218-346): 2.28e-14: 75.2: 35.61
+	Hs
		798194 Q5RIP0_HUMAN (1-345): 2.27e-160: 454: 77.17		KI2L3_HUMAN (218-346): 2.28e-14: 75.2: 35.61
+	Hs
		798173 Q5RIP0_HUMAN (1-345): 2.27e-160: 454: 77.17		KI2L2_HUMAN (218-346): 5.9e-14: 74: 34.85
+	Hs
		798148 Q5RIP0_HUMAN (1-345): 2.27e-160: 454: 77.17		KI2L1_HUMAN (218-346): 2.66e-13: 72.1: 33.33