HitPredict

Interactor 1: HLAF (P30511)
HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene: HLA-F

Interactor 2: LIRB2 (Q8N423)
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)
Gene: LILRB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24018270
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~ig, C1-set~Ig_2, MHC_I~ig
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0006955 - immune response GO:0009986 - cell surface GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 346 Hs			1 597
+	Hs
		1232786 Q95J06_HUMAN (1-345): 6.76e-175: 491: 80.87		LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00
+	Hs
		382478 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00
+	Hs
		1130837 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		LIRB2_HUMAN (1-597): 8.63e-135: 407: 100.00
+	Hs
		1245576 Q95J06_HUMAN (1-345): 6.76e-175: 491: 80.87		LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92
+	Hs
		382485 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92
+	Hs
		1130838 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		LIRB1_HUMAN (1-597): 1.37e-123: 380: 76.92
+	Hs
		1060406 Q95J06_HUMAN (1-345): 6.76e-175: 491: 80.87		KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93
+	Hs
		382420 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93
+	Hs
		1060403 Q5SUL5_HUMAN (1-345): 2.11e-167: 472: 79.71		KI3S1_HUMAN (1-344): 4.79e-67: 224: 37.93
+	Hs
		382484 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		LIRB4_HUMAN (1-238): 2.36e-57: 200: 48.32
+	Hs
		798280 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		KI2S4_HUMAN (119-337): 4.16e-51: 180: 41.82
+	Hs
		798148 Q5RIP0_HUMAN (1-345): 2.27e-160: 454: 77.17		KI2L1_HUMAN (117-337): 5.21e-48: 173: 40.54
+	Hs
		798146 Q5D1W8_HUMAN (1-345): 7.6e-159: 451: 77.46		KI2L1_HUMAN (117-337): 5.21e-48: 173: 40.54
+	Hs
		798195 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		KI2L3_HUMAN (117-334): 1.26e-29: 121: 40.18
+	Hs
		798194 Q5RIP0_HUMAN (1-345): 2.27e-160: 454: 77.17		KI2L3_HUMAN (117-334): 1.26e-29: 121: 40.18
+	Hs
		798173 Q5RIP0_HUMAN (1-345): 2.27e-160: 454: 77.17		KI2L2_HUMAN (117-334): 7.81e-29: 119: 39.09
+	Hs
		798171 Q5D1W8_HUMAN (1-345): 7.6e-159: 451: 77.46		KI2L2_HUMAN (117-334): 7.81e-29: 119: 39.09
+	Hs
		47499 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		A0A8I5QEB2_HUMAN (317-447): 2.68e-18: 89.3: 32.06
+	Hs
		382341 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		KI3L2_HUMAN (323-597): 2.69e-16: 83.5: 20.19
+	Hs
		798244 Q5S3G3_HUMAN (1-345): 1.47e-169: 478: 80.58		KI3L2_HUMAN (323-597): 2.69e-16: 83.5: 20.19