HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0007165 - signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 246
+	Hs
		674386 UFO_HUMAN (1-894): 0: 780: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909494 MERTK_HUMAN (7-861): 0: 588: 40.53		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683304 MERTK_HUMAN (7-861): 0: 588: 40.53		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		646846 MERTK_HUMAN (7-861): 0: 588: 40.53		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		411315 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		411316 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Mm
		554972 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02
+	Hs
		441479 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909466 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683284 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		926953 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		646822 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Mm
		554970 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		1433G_MOUSE (3-246): 1.91e-109: 317: 75.40
+	Hs
		601470 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		601493 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		441444 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		904469 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		904472 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		981860 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		683980 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62