HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: UTRN (P46939)
Utrophin (Dystrophin-related protein 1) (DRP-1)
Gene: UTRN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~fn3, CH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 3433
+	Rn
		102506 INSR_RAT (276-851): 1.26e-134: 437: 27.83		UTRN_RAT (1-3433): 0: 1098: 86.31
+	Hs
		609206 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		UTRN_HUMAN (1-3433): 0: 1138: 100.00
+	Hs
		507905 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		UTRN_HUMAN (1-3433): 0: 1138: 100.00
+	Hs
		665392 EPHA3_HUMAN (2-831): 0: 646: 19.34		DYST_HUMAN (1753-2928): 7.52e-11: 70.9: 8.33
+	Hs
		665216 EPHA2_HUMAN (3-837): 0: 604: 19.66		DYST_HUMAN (1753-2928): 7.52e-11: 70.9: 8.33
+	Hs
		600556 EPHA1_HUMAN (1-837): 0: 555: 20.58		DYST_HUMAN (1753-2928): 7.52e-11: 70.9: 8.33
+	Rn
		88537 INSR_RAT (276-851): 1.26e-134: 437: 27.83		D3ZC56_RAT (767-2962): 2.78e-40: 168: 11.75
+	Hs
		508288 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		DTNA_HUMAN (2841-3425): 1.78e-90: 315: 23.38
+	Mm
		555047 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		MACF1_MOUSE (925-3378): 9.59e-29: 130: 11.29
+	Mm
		555045 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		PLEC_MOUSE (1861-3399): 6.7e-15: 84.4: 10.08
+	Hs
		713787 RYK_HUMAN (521-810): 4.45e-57: 209: 37.63		DYST_HUMAN (1753-2928): 7.52e-11: 70.9: 8.33
+	Hs
		601499 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		DYST_HUMAN (1753-2928): 7.52e-11: 70.9: 8.33
+	Hs
		508011 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		PLEC_HUMAN (1861-3399): 1.04e-13: 80.5: 10.71