HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0043066 - negative regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 1748
+	Hs
		159179 EPHA4_HUMAN (2-836): 0: 637: 19.40		CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66
+	Hs
		159214 EPHA7_HUMAN (2-837): 0: 621: 19.50		CSKP_HUMAN (217-806): 6.5e-86: 305: 14.66
+	Hs
		1072518 EPHA7_HUMAN (2-837): 0: 621: 19.50		MPP7_HUMAN (310-807): 3.29e-83: 287: 14.96
+	Hs
		674412 UFO_HUMAN (1-894): 0: 780: 100.00		DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54
+	Hs
		665393 EPHA3_HUMAN (2-831): 0: 646: 19.34		PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63
+	Hs
		872638 EPHA4_HUMAN (2-836): 0: 637: 19.40		PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63
+	Hs
		872431 EPHA5_HUMAN (2-812): 0: 622: 20.39		PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63
+	Hs
		1020163 EPHA7_HUMAN (2-837): 0: 621: 19.50		PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63
+	Hs
		872639 EPHA4_HUMAN (2-836): 0: 637: 19.40		DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54
+	Hs
		665589 EPHB2_HUMAN (2-837): 0: 605: 19.58		PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63
+	Hs
		665228 EPHA2_HUMAN (3-837): 0: 604: 19.66		PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63
+	Hs
		872433 EPHA5_HUMAN (2-812): 0: 622: 20.39		DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54
+	Hs
		1021499 EPHA7_HUMAN (2-837): 0: 621: 19.50		DLG1_HUMAN (263-512): 3.61e-17: 90: 16.54
+	Hs
		872674 EPHA4_HUMAN (2-836): 0: 637: 19.40		UNC5B_HUMAN (1634-1718): 3.49e-11: 70.5: 44.71
+	Hs
		665293 EPHA2_HUMAN (3-837): 0: 604: 19.66		DLG5_HUMAN (262-508): 3.83e-17: 90.3: 21.43
+	Hs
		872459 EPHA5_HUMAN (2-812): 0: 622: 20.39		UNC5B_HUMAN (1634-1718): 3.49e-11: 70.5: 44.71
+	Hs
		1072543 EPHA7_HUMAN (2-837): 0: 621: 19.50		UNC5B_HUMAN (1634-1718): 3.49e-11: 70.5: 44.71
+	Hs
		665628 EPHB2_HUMAN (2-837): 0: 605: 19.58		UNC5B_HUMAN (1634-1718): 3.49e-11: 70.5: 44.71
+	Hs
		600564 EPHA1_HUMAN (1-837): 0: 555: 20.58		PTN13_HUMAN (20-492): 4.02e-23: 110: 16.63
+	Hs
		665499 EPHA8_HUMAN (2-824): 0: 590: 19.20		UNC5B_HUMAN (1634-1718): 3.49e-11: 70.5: 44.71