HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: SNX1 (Q13596)
Sorting nexin-1
Gene: SNX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 522
+	Hs
		240370 EPHA5_HUMAN (2-812): 0: 622: 20.39		SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95
+	Hs
		411380 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00
+	Hs
		872507 EPHA5_HUMAN (2-812): 0: 622: 20.39		SNX6_HUMAN (145-520): 1.81e-73: 240: 20.46
+	Hs
		240332 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95
+	Rn
		71355 INSR_RAT (276-851): 1.26e-134: 437: 27.83		B2RYP4_RAT (10-522): 8.39e-125: 376: 58.95
+	Mm
		546277 INSR_MOUSE (232-851): 2.75e-135: 439: 26.37		SNX9_MOUSE (4-518): 6.29e-96: 304: 13.88
+	Hs
		307875 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		SNX4_HUMAN (95-516): 2.25e-75: 246: 14.75
+	Hs
		411539 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45
+	Hs
		411527 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		SNX6_HUMAN (145-520): 1.81e-73: 240: 20.46
+	Rn
		69429 INSR_RAT (276-851): 1.26e-134: 437: 27.83		B0BMY2_RAT (118-249): 1.83e-34: 128: 25.00
+	Hs
		507986 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00
+	Hs
		435636 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		SNX1_HUMAN (1-522): 8.2e-149: 438: 100.00
+	Ce
		371325 ABL1_CAEEL (531-826): 2.32e-56: 213: 41.75		LST4_CAEEL (10-519): 2.56e-77: 255: 16.32
+	Hs
		445888 ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27		SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45
+	Hs
		240342 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95
+	Hs
		240333 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95
+	Hs
		435813 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45
+	Hs
		508266 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SNX6_HUMAN (145-520): 1.81e-73: 240: 20.46
+	Hs
		435805 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		SNX6_HUMAN (145-520): 1.81e-73: 240: 20.46
+	Hs
		609637 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		SNX11_HUMAN (137-268): 7.22e-31: 122: 31.34