HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: GAS6 (Q14393)
Growth arrest-specific protein 6 (GAS-6) (AXL receptor tyrosine kinase ligand)
Gene: GAS6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.952

The method score is based on:

Property Details
Experiments 8939948, 32707033, 36736316, 7854420, 12218057, 16362042
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, surface plasmon resonance, solid phase assay
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_CA~fn3, Ig_3~Laminin_G_1
Common GO terms GO:0001764 - neuron migration
GO:0001786 - phosphatidylserine binding
GO:0001961 - positive regulation of cytokine-mediated signaling pathway
GO:0005615 - extracellular space
GO:0006909 - phagocytosis
and 12 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 894
Hs

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Last updated: 15 Jul 2024