HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 1233
+	Hs
		311485 UFO_HUMAN (1-894): 0: 780: 100.00		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		674568 UFO_HUMAN (1-894): 0: 780: 100.00		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		674563 UFO_HUMAN (1-894): 0: 780: 100.00		MYH2_HUMAN (495-1125): 5.14e-20: 99: 9.49
+	Hs
		1018374 MERTK_HUMAN (7-861): 0: 588: 40.53		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		311476 EPHA1_HUMAN (1-837): 0: 555: 20.58		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		600709 EPHA1_HUMAN (1-837): 0: 555: 20.58		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		311530 TIE2_HUMAN (16-809): 3.58e-164: 510: 23.90		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		665375 EPHA3_HUMAN (2-831): 0: 646: 19.34		MYH9_HUMAN (49-760): 1.43e-25: 117: 11.62
+	Hs
		981873 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		609288 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		311462 ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		445885 ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		981936 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		311477 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		311465 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		609617 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Mm
		555031 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		MYH9_MOUSE (720-1139): 9.89e-18: 91.7: 10.26