HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 1104
+	Hs
		872481 EPHA5_HUMAN (2-812): 0: 622: 20.39		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		665519 EPHA8_HUMAN (2-824): 0: 590: 19.20		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		411488 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		445875 ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		508173 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		435743 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		ESYT1_HUMAN (1-1104): 0: 874: 100.00
+	Hs
		48274 UFO_HUMAN (1-894): 0: 780: 100.00		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		48271 EPHA2_HUMAN (3-837): 0: 604: 19.66		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		508104 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SYT2_HUMAN (205-455): 5.33e-25: 111: 14.54