HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: E41L1 (Q9H4G0)
Band 4.1-like protein 1 (Erythrocyte membrane protein band 4.1-like 1) (Neuronal protein 4.1) (4.1N)
Gene: EPB41L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 881
+	Hs
		204618 UFO_HUMAN (1-894): 0: 780: 100.00		E41L2_HUMAN (3-875): 0: 561: 42.93
+	Hs
		674532 UFO_HUMAN (1-894): 0: 780: 100.00		E41L5_HUMAN (60-763): 1.14e-151: 465: 25.89
+	Hs
		665337 EPHA2_HUMAN (3-837): 0: 604: 19.66		E41LA_HUMAN (94-761): 3.88e-129: 405: 24.60
+	Hs
		665554 EPHB2_HUMAN (2-837): 0: 605: 19.58		MERL_HUMAN (87-655): 2.08e-128: 400: 22.05
+	Hs
		665158 EPHA2_HUMAN (3-837): 0: 604: 19.66		MERL_HUMAN (87-655): 2.08e-128: 400: 22.05
+	Hs
		719689 EPHA5_HUMAN (2-812): 0: 622: 20.39		RADI_HUMAN (94-672): 2.79e-119: 376: 21.44
+	Hs
		546943 EPHA2_HUMAN (3-837): 0: 604: 19.66		EZRI_HUMAN (94-672): 1.1e-123: 387: 22.83
+	Hs
		665555 EPHB2_HUMAN (2-837): 0: 605: 19.58		RADI_HUMAN (94-672): 2.79e-119: 376: 21.44
+	Hs
		505564 UFO_HUMAN (1-894): 0: 780: 100.00		EPB41_HUMAN (528-872): 1.64e-35: 147: 21.88
+	Hs
		546957 TIE1_HUMAN (16-809): 4.24e-158: 494: 21.82		EZRI_HUMAN (94-672): 1.1e-123: 387: 22.83
+	Hs
		411302 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		PTN3_HUMAN (69-717): 3e-138: 436: 24.14
+	Hs
		441435 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		PTN3_HUMAN (69-717): 3e-138: 436: 24.14
+	Hs
		983673 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		E41L5_HUMAN (60-763): 1.14e-151: 465: 25.89
+	Mm
		101476 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		FARP1_MOUSE (75-603): 1.44e-127: 411: 31.26
+	Hs
		441450 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		MERL_HUMAN (87-655): 2.08e-128: 400: 22.05
+	Hs
		983700 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		TLN1_HUMAN (42-879): 3.41e-119: 401: 10.75
+	Hs
		719456 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		MERL_HUMAN (87-655): 2.08e-128: 400: 22.05
+	Hs
		547018 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		EZRI_HUMAN (94-672): 1.1e-123: 387: 22.83
+	Hs
		299238 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		FARP2_HUMAN (71-603): 8.14e-122: 396: 30.24
+	Hs
		505551 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		EPB41_HUMAN (528-872): 1.64e-35: 147: 21.88