HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: LRC40 (Q9H9A6)
Leucine-rich repeat-containing protein 40
Gene: LRRC40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ig_3~LRR_8, LRR_8~PK_Tyr_Ser-Thr
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 602
+	Hs
		674422 UFO_HUMAN (1-894): 0: 780: 100.00		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		674510 UFO_HUMAN (1-894): 0: 780: 100.00		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		1049958 EPHA7_HUMAN (2-837): 0: 621: 19.50		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		665600 EPHB2_HUMAN (2-837): 0: 605: 19.58		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		665420 EPHA3_HUMAN (2-831): 0: 646: 19.34		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		232788 EPHA2_HUMAN (3-837): 0: 604: 19.66		PHLP1_HUMAN (82-555): 7.84e-25: 112: 25.00
+	Hs
		872694 EPHA4_HUMAN (2-836): 0: 637: 19.40		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		872473 EPHA5_HUMAN (2-812): 0: 622: 20.39		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		1072577 EPHA7_HUMAN (2-837): 0: 621: 19.50		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		665318 EPHA2_HUMAN (3-837): 0: 604: 19.66		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		441501 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		169176 MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		507995 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		435639 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		SCRIB_HUMAN (364-601): 3.28e-37: 150: 21.85
+	Hs
		601574 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		169196 MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26		ERBIN_HUMAN (83-237): 3.33e-14: 78.2: 31.61
+	Hs
		169200 MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26		LRRC1_HUMAN (41-220): 2.84e-14: 77.8: 31.11
+	Hs
		508286 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		MFHA1_HUMAN (404-585): 1.78e-14: 79: 30.22