HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: SWP70 (Q9UH65)
Switch-associated protein 70 (SWAP-70)
Gene: SWAP70

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 585
+	Hs
		674551 UFO_HUMAN (1-894): 0: 780: 100.00		EP15R_HUMAN (431-585): 1.02e-13: 76.4: 12.26
+	Hs
		665162 EPHA2_HUMAN (3-837): 0: 604: 19.66		EPS15_HUMAN (175-576): 8.99e-48: 181: 16.14
+	Hs
		665608 EPHB2_HUMAN (2-837): 0: 605: 19.58		ITSN1_HUMAN (174-585): 6.34e-40: 158: 14.12
+	Hs
		305100 EPHA4_HUMAN (2-836): 0: 637: 19.40		RIMB1_HUMAN (228-567): 1.06e-16: 86.4: 13.12
+	Hs
		665375 EPHA3_HUMAN (2-831): 0: 646: 19.34		MYH9_HUMAN (237-570): 5.41e-09: 61.4: 13.65
+	Hs
		600669 EPHA1_HUMAN (1-837): 0: 555: 20.58		TARA_HUMAN (261-583): 9.46e-11: 67.2: 13.89
+	Hs
		983668 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		DEFI6_HUMAN (3-542): 4.36e-118: 365: 46.00
+	Hs
		111149 I6L996_HUMAN (527-851): 5.42e-57: 210: 36.83		DEFI6_HUMAN (3-542): 4.36e-118: 365: 46.00
+	Hs
		983688 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		SWP70_HUMAN (1-585): 1.36e-117: 362: 100.00
+	Hs
		983637 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		CIP2A_HUMAN (283-561): 1.02e-40: 160: 17.99
+	Mm
		554992 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		MRCKA_MOUSE (283-581): 1.54e-13: 76: 12.78
+	Mm
		555045 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		PLEC_MOUSE (295-575): 4.14e-09: 62.1: 16.84
+	Mm
		555031 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		MYH9_MOUSE (286-581): 6.49e-09: 61.4: 15.41
+	Hs
		508022 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ITSN1_HUMAN (174-585): 6.34e-40: 158: 14.12
+	Hs
		601589 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		TARA_HUMAN (261-583): 9.46e-11: 67.2: 13.89
+	Hs
		508190 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		TARA_HUMAN (261-583): 9.46e-11: 67.2: 13.89
+	Hs
		508011 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		PLEC_HUMAN (316-521): 1.19e-10: 67.1: 22.28