HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.578

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~fn3
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 1771
+	Hs
		665439 EPHA3_HUMAN (2-831): 0: 646: 19.34		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		872504 EPHA5_HUMAN (2-812): 0: 622: 20.39		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		665360 EPHA2_HUMAN (3-837): 0: 604: 19.66		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		713887 RYK_HUMAN (521-810): 4.45e-57: 209: 37.63		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		601612 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		KDIS_HUMAN (13-1771): 0: 2634: 100.00
+	Hs
		665591 EPHB2_HUMAN (2-837): 0: 605: 19.58		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		665581 EPHB2_HUMAN (2-837): 0: 605: 19.58		ANK2_HUMAN (3-233): 5.93e-53: 208: 25.11
+	Hs
		600670 EPHA1_HUMAN (1-837): 0: 555: 20.58		TNKS2_HUMAN (242-532): 3.88e-66: 248: 18.10
+	Hs
		310035 EPHA1_HUMAN (1-837): 0: 555: 20.58		TNKS1_HUMAN (2-231): 3.1e-56: 217: 23.43
+	Hs
		600539 EPHA1_HUMAN (1-837): 0: 555: 20.58		DAPK1_HUMAN (4-305): 4.92e-35: 149: 31.58
+	Mm
		103592 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		ANK3_MOUSE (206-542): 2.22e-68: 258: 19.04
+	Hs
		713794 RYK_HUMAN (521-810): 4.45e-57: 209: 37.63		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		507831 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ANK1_HUMAN (96-531): 5.46e-92: 334: 20.00
+	Hs
		507971 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ANK3_HUMAN (206-542): 1.55e-67: 256: 18.50
+	Hs
		983635 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		ANKH1_HUMAN (359-505): 5.6e-23: 109: 12.16
+	Hs
		507954 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ANK2_HUMAN (3-233): 5.93e-53: 208: 25.11