HitPredict

Interactor 1: SC6A1 (P30531)
Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1)
Gene: SLC6A1

Interactor 2: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	9698305, 11960023, 11017172
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030424 - axon
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 599 Hs			1 288
+	Mm
		681240 SC6A1_MOUSE (1-599): 0: 770: 98.00		STX1B_MOUSE (1-288): 5.2e-85: 258: 83.33
+	Hs
		1084015 SC6A5_HUMAN (1-577): 0: 683: 43.88		STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00
+	Hs
		681224 SC6A4_HUMAN (3-580): 0: 660: 42.03		STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00
+	Mm
		192850 SC6A3_MOUSE (2-583): 0: 645: 43.15		STX1A_MOUSE (1-288): 3.69e-86: 261: 98.26
+	Hs
		968115 SC6A3_HUMAN (2-583): 0: 650: 43.41		STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00
+	Hs
		816330 SC6A9_HUMAN (10-577): 0: 640: 42.37		STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00
+	Hs
		621435 SC6A2_HUMAN (34-576): 0: 639: 46.21		STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00
+	Ce
		183453 NTDO_CAEEL (3-596): 0: 592: 37.22		STX1A_CAEEL (2-283): 8.04e-75: 232: 64.31
+	Hs
		681200 SC6A6_HUMAN (21-575): 0: 620: 51.15		STX4_HUMAN (1-287): 1.22e-63: 203: 43.58
+	Hs
		815772 SC6A8_HUMAN (2-573): 0: 620: 50.51		STX4_HUMAN (1-287): 1.22e-63: 203: 43.58
+	Hs
		178410 SC6A6_HUMAN (21-575): 0: 620: 51.15		STX7_HUMAN (37-286): 6.99e-50: 167: 25.30
+	Hs
		178429 SC6A8_HUMAN (2-573): 0: 620: 50.51		STX7_HUMAN (37-286): 6.99e-50: 167: 25.30
+	Hs
		1017790 S6A15_HUMAN (19-555): 3.7e-143: 433: 25.37		STX4_HUMAN (1-287): 1.22e-63: 203: 43.58
+	Hs
		1205370 S6A15_HUMAN (19-555): 3.7e-143: 433: 25.37		STX12_HUMAN (26-271): 2.32e-51: 171: 24.50
+	Hs
		178774 S6A15_HUMAN (19-555): 3.7e-143: 433: 25.37		STX7_HUMAN (37-286): 6.99e-50: 167: 25.30