HitPredict

Interactor 1: PSB5 (P30655)
Probable proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit pts1) (Multicatalytic endopeptidase complex subunit pts1) (Proteasome component pts1)
Gene: pts1

Interactor 2: PSA4 (Q10329)
Probable proteasome subunit alpha type-4
Gene: pre6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	20133687, 24938783
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0004175 - endopeptidase activity GO:0005634 - nucleus GO:0005829 - cytosol GO:0019774 - proteasome core complex, beta-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Sp			1 259
+	Sp
		1013784 PSA5_SCHPO (20-263): 4.01e-89: 266: 16.47		PSA4_SCHPO (1-259): 2.44e-102: 299: 100.00
+	Sp
		675393 PSB5_SCHPO (1-272): 1.67e-90: 270: 100.00		PSA5_SCHPO (2-237): 5.79e-94: 278: 32.79
+	Hs
		156230 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		156228 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		637325 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Ss
		94704 F2Z5K2_PIG (20-260): 1.08e-87: 262: 15.94		F2Z5L7_PIG (2-259): 1.01e-93: 278: 27.27
+	Hs
		656149 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Hs
		656276 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSMA8_HUMAN (2-230): 1.66e-93: 277: 52.74
+	Hs
		156224 PSA2_HUMAN (24-261): 8.33e-84: 252: 13.22		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		637323 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		637316 PSA2_HUMAN (24-261): 8.33e-84: 252: 13.22		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Hs
		656189 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Sc
		675422 PSB5_YEAST (7-270): 8.81e-84: 254: 61.89		PSA4_YEAST (1-232): 5.22e-93: 275: 58.48
+	Dm
		611647 PSA5_DROME (20-261): 4.21e-86: 258: 18.11		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Sc
		675397 PSB5_YEAST (7-270): 8.81e-84: 254: 61.89		PSA5_YEAST (2-245): 1.62e-91: 272: 32.54
+	Hv
		1358195 PSA1_HALVD (18-259): 1.21e-84: 255: 19.36		PSA1_HALVD (4-242): 6.51e-90: 268: 36.74
+	Hs
		656051 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Dm
		771303 PSA5_DROME (20-261): 4.21e-86: 258: 18.11		PSA2_DROME (4-212): 3.06e-48: 161: 37.92
+	Hs
		637631 PSA5_HUMAN (20-260): 1.08e-87: 262: 15.94		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10
+	Hs
		637629 PSB8_HUMAN (10-265): 6.93e-85: 256: 49.61		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10