HitPredict

Interactor 1: RENT1 (P30771)
ATP-dependent helicase NAM7 (EC 3.6.4.12) (EC 3.6.4.13) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1)
Gene: NAM7

Interactor 2: RENT1 (P30771)
ATP-dependent helicase NAM7 (EC 3.6.4.12) (EC 3.6.4.13) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1)
Gene: NAM7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 8816462, 14759368
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_11~AAA_11, AAA_11~AAA_12, AAA_11~UPF1_1B_dom, AAA_12~AAA_12, AAA_12~UPF1_1B_dom, AAA_12~UPF1_Zn_bind, UPF1_Zn_bind~UPF1_Zn_bind
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003697 - single-stranded DNA binding
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
and 15 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 971
Sc

1 971
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024