HitPredict

Interactor 1: RENT1 (P30771)
ATP-dependent helicase NAM7 (EC 3.6.4.12) (EC 3.6.4.13) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1)
Gene: NAM7

Interactor 2: HRP1 (Q99383)
Nuclear polyadenylated RNA-binding protein 4 (Cleavage factor IB) (CFIB) (Heterogeneous nuclear ribonucleoprotein 1)
Gene: HRP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	10882134, 16611983
Identification Methods	coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 971 Sc			1 534
+	Sc
		376676 RENT1_YEAST (1-971): 0: 1317: 100.00		PABP_YEAST (33-514): 1.08e-49: 182: 13.94
+	Hs
		1272317 RENT1_HUMAN (37-902): 0: 1142: 53.69		ROAA_HUMAN (91-361): 1.44e-73: 238: 30.94
+	Hs
		852119 RENT1_HUMAN (37-902): 0: 1142: 53.69		ROA3_HUMAN (152-327): 7.1e-69: 228: 38.80
+	Hs
		1272293 RENT1_HUMAN (37-902): 0: 1142: 53.69		MSI2H_HUMAN (140-474): 1.17e-55: 191: 25.29
+	Hs
		609980 RENT1_HUMAN (37-902): 0: 1142: 53.69		ROA2_HUMAN (139-242): 1.7e-23: 103: 31.43
+	Hs
		516622 RENT1_HUMAN (37-902): 0: 1142: 53.69		PABP1_HUMAN (233-328): 5.67e-15: 80: 22.68
+	Sc
		376894 SEN1_YEAST (222-879): 1.13e-156: 512: 23.04		PABP_YEAST (33-514): 1.08e-49: 182: 13.94
+	Hs
		1031468 MOV10_HUMAN (216-854): 3.29e-158: 493: 24.21		PABP4_HUMAN (233-328): 1.27e-15: 81.9: 20.62
+	Hs
		516699 MOV10_HUMAN (216-854): 3.29e-158: 493: 24.21		PABP1_HUMAN (233-328): 5.67e-15: 80: 22.68