HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: GPN1 (P47122)
GPN-loop GTPase 1 (EC 3.6.5.-) (Essential PCL1-interacting ATPase 1) (GPN-loop GTPase NPA3) (Nucleolar preribosomal-associated protein 3)
Gene: NPA3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26673895, 21844196
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1084 Sc			1 385
+	Xl
		1108834 Q6NS03_XENLA (3-1084): 0: 852: 46.77		Q3KQ86_XENLA (6-366): 4.76e-166: 470: 47.17
+	Hs
		163316 XPO1_HUMAN (3-1084): 0: 854: 46.40		GPN1_HUMAN (6-360): 9.49e-144: 414: 48.63
+	Hs
		163299 XPO1_HUMAN (3-1084): 0: 854: 46.40		GPN2_HUMAN (8-255): 5.41e-95: 288: 21.88
+	Xl
		1118793 Q6NS03_XENLA (3-1084): 0: 852: 46.77		GPN3_XENLA (1-287): 1.07e-94: 286: 21.99
+	Hs
		163428 XPO1_HUMAN (3-1084): 0: 854: 46.40		GPN3_HUMAN (1-280): 8.58e-94: 283: 22.97
+	Sc
		676396 XPO1_YEAST (1-1084): 0: 833: 100.00		GPN3_YEAST (1-257): 6.46e-97: 291: 26.64
+	Xl
		1146318 Q6NS03_XENLA (3-1084): 0: 852: 46.77		GPN2_XENLA (8-255): 6.03e-87: 267: 20.95
+	Sc
		676441 XPO1_YEAST (1-1084): 0: 833: 100.00		GPN2_YEAST (7-255): 3.58e-88: 271: 27.00
+	Mm
		1257421 XPO7_MOUSE (11-1030): 1.87e-146: 468: 13.68		GPN1_MOUSE (6-362): 8.39e-142: 409: 47.54
+	Mm
		1322018 XPO7_MOUSE (11-1030): 1.87e-146: 468: 13.68		GPN3_MOUSE (1-287): 5.79e-96: 289: 21.99
+	Mm
		1257570 XPO7_MOUSE (11-1030): 1.87e-146: 468: 13.68		GPN2_MOUSE (8-255): 5.23e-95: 288: 22.13
+	Sp
		1358057 YNR7_SCHPO (14-1011): 2.95e-100: 340: 14.97		GPN2_SCHPO (7-255): 1.23e-83: 259: 22.01