HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: AP3D (Q08951)
AP-3 complex subunit delta (Adaptor-related protein complex 3 subunit delta) (Delta-adaptin 3) (Delta-adaptin)
Gene: APL5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26673895, 32840906
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1084 Sc			1 932
+	Hs
		162233 XPO1_HUMAN (3-1084): 0: 854: 46.40		AP1G1_HUMAN (26-846): 9.09e-176: 532: 15.78
+	Xl
		1151538 Q6NS03_XENLA (3-1084): 0: 852: 46.77		Q6GPE1_XENLA (26-835): 2.86e-171: 520: 15.87
+	Xl
		50503 Q6NS03_XENLA (3-1084): 0: 852: 46.77		A1L2H5_XENLA (39-713): 9.52e-158: 489: 15.00
+	Hs
		150134 XPO1_HUMAN (3-1084): 0: 854: 46.40		AP3D1_HUMAN (21-919): 1.98e-151: 479: 26.50
+	Hs
		163409 XPO1_HUMAN (3-1084): 0: 854: 46.40		COPG2_HUMAN (23-908): 7.53e-155: 479: 13.21
+	Xl
		1150313 Q6NS03_XENLA (3-1084): 0: 852: 46.77		COPG2_XENLA (23-908): 1.98e-149: 465: 12.61
+	Hs
		162312 XPO1_HUMAN (3-1084): 0: 854: 46.40		AP2A1_HUMAN (25-846): 5.7e-147: 462: 14.99
+	Hs
		163533 XPO1_HUMAN (3-1084): 0: 854: 46.40		COPG1_HUMAN (23-906): 5.15e-148: 462: 12.51
+	Xl
		1155621 Q6NS03_XENLA (3-1084): 0: 852: 46.77		Q6P7I2_XENLA (23-906): 5.15e-148: 462: 12.63
+	Hs
		162272 XPO1_HUMAN (3-1084): 0: 854: 46.40		AP1G2_HUMAN (27-835): 3.38e-148: 459: 14.62
+	Hs
		162606 XPO1_HUMAN (3-1084): 0: 854: 46.40		AP2B1_HUMAN (39-776): 2.38e-146: 459: 13.77
+	Hs
		162675 XPO1_HUMAN (3-1084): 0: 854: 46.40		AP1B1_HUMAN (39-701): 9.88e-146: 458: 14.58
+	Xl
		1155726 Q6NS03_XENLA (3-1084): 0: 852: 46.77		Q7ZYG7_XENLA (39-662): 4.14e-145: 456: 14.35
+	Hs
		163469 XPO1_HUMAN (3-1084): 0: 854: 46.40		AP4E1_HUMAN (23-741): 1.03e-117: 388: 19.33
+	Sc
		676449 XPO1_YEAST (1-1084): 0: 833: 100.00		AP1G1_YEAST (25-721): 7.34e-73: 259: 18.48
+	Sc
		675978 XPO1_YEAST (1-1084): 0: 833: 100.00		AP2A_YEAST (25-820): 1.96e-48: 188: 17.17