HitPredict

Interactor 1: CTR1 (P30825)
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene: SLC7A1

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 31871319
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 629 Hs			1 192
+	Hs
		676533 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		545221 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		676617 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		676536 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		676528 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		676530 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		436173 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		854874 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		545280 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		854912 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		854865 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		854876 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		854866 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		854869 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		436219 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		564457 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		925480 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		951194 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		894268 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		900749 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32