HitPredict

Interactor 1: CTR1 (P30825)
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene: SLC7A1

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 629 Hs			1 192
+	Hs
		545221 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		676617 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		676527 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		676536 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		676528 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		676530 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436173 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		854874 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564457 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545280 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		854912 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		854865 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		854876 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		854866 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		854869 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436219 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		925480 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		951194 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		894268 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900749 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98