HitPredict

Interactor 1: CTR1 (P30825)
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene: SLC7A1

Interactor 2: S22AI (Q96BI1)
Solute carrier family 22 member 18 (Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein) (Efflux transporter-like protein) (Imprinted multi-membrane-spanning polyspecific transporter-related protein 1) (Organic cation transporter-like protein 2) (ORCTL-2) (Solute carrier family 22 member 1-like) (Tumor-suppressing STF cDNA 5 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein) (p45-Beckwith-Wiedemann region 1 A) (p45-BWR1A)
Gene: SLC22A18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0016324 - apical plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 629 Hs			1 424
+	Hs
		676580 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		MFSD8_HUMAN (22-404): 5.22e-45: 165: 15.40
+	Hs
		868014 CTR3_HUMAN (1-621): 1.21e-138: 419: 59.42		VMAT1_HUMAN (61-423): 2.01e-46: 169: 17.57
+	Hs
		676537 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		VMAT2_HUMAN (26-210): 1.51e-12: 71.3: 16.13
+	Hs
		985369 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		VMAT2_HUMAN (26-210): 1.51e-12: 71.3: 16.13