HitPredict

Interactor 1: RPB2 (P30876)
DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) (RNA-directed RNA polymerase II subunit RPB2) (EC 2.7.7.48)
Gene: POLR2B

Interactor 2: RPB9 (P36954)
DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5)
Gene: POLR2I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 24981860, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_POL_M_15KD~RNA_pol_Rpb2_1, RNA_pol_Rpb2_1~TFIIS_C, RNA_pol_Rpb2_6~TFIIS_C
Common GO terms GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005665 - RNA polymerase II, core complex
GO:0006366 - transcription by RNA polymerase II
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1174
Hs

1 125
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Last updated: 15 Jul 2024