Interactor 1: CENPX (A8MT69)
Centromere protein X (CENP-X) (FANCM-associated histone fold protein 2) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Retinoic acid-inducible gene D9 protein homolog) (Stimulated by retinoic acid gene 13 protein homolog)
Gene: CENPX

Interactor 2: CENPS (Q8N2Z9)
Centromere protein S (CENP-S) (Apoptosis-inducing TAF9-like domain-containing protein 1) (FANCM-associated histone fold protein 1) (FANCM-interacting histone fold protein 1) (Fanconi anemia-associated polypeptide of 16 kDa)
Gene: CENPS

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 20347428, 24699063, 20347429, 24390579, 23886707, 22510687, 33961781, 24522885, 22304917
Identification Methods affinity chromatography technology, two hybrid, pull down, x-ray crystallography, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, molecular sieving, x ray scattering
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-S~CENP-X
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0000785 - chromatin
GO:0000939 - inner kinetochore
GO:0003677 - DNA binding
GO:0005634 - nucleus
and 9 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 81
Hs

1 138
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024