HitPredict

Interactor 1: DLG1 (P31007)
Disks large 1 tumor suppressor protein (Dlg)
Gene: DLG1

Interactor 2: DSH (P51140)
Segment polarity protein dishevelled
Gene: DSH

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25461409, 27536874
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0005886 - plasma membrane GO:0007391 - dorsal closure GO:0030707 - follicle cell of egg chamber development GO:0045179 - apical cortex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 970 Dm			1 623
+	Rn
		1144014 DLG1_RAT (1-970): 0: 632: 47.72		DLG2_RAT (43-615): 1.61e-79: 270: 13.41
+	Hs
		1021501 DLG1_HUMAN (1-970): 0: 634: 48.43		DLG2_HUMAN (43-615): 1.36e-77: 265: 13.74
+	Hs
		1021482 DLG1_HUMAN (1-970): 0: 634: 48.43		DLG1_HUMAN (30-615): 4.97e-67: 237: 14.43
+	Dm
		677679 DLG1_DROME (1-970): 0: 703: 100.00		DLG1_DROME (9-615): 2.15e-40: 160: 16.46
+	Hs
		1021542 DLG1_HUMAN (1-970): 0: 634: 48.43		DLG3_HUMAN (89-615): 5.93e-59: 213: 13.15
+	Rn
		1144010 DLG1_RAT (1-970): 0: 632: 47.72		DLG3_RAT (110-615): 5.17e-59: 214: 13.13
+	Mm
		1113136 Q3UP61_MOUSE (1-970): 0: 634: 48.66		DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13
+	Mm
		1143387 DLG1_MOUSE (1-970): 0: 634: 48.12		DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13
+	Rn
		677787 DLG1_RAT (1-970): 0: 632: 47.72		DLG4_RAT (101-609): 1.3e-57: 208: 12.70
+	Hs
		1021538 DLG1_HUMAN (1-970): 0: 634: 48.43		PARD3_HUMAN (47-405): 2.97e-40: 160: 16.02
+	Ce
		105565 DLG1_CAEEL (5-965): 6.08e-163: 505: 35.13		Q18239_CAEEL (10-496): 3.25e-77: 262: 30.62
+	Ce
		105570 DLG1_CAEEL (5-965): 6.08e-163: 505: 35.13		MIG5_CAEEL (10-521): 2.64e-57: 206: 25.00
+	Rn
		1144009 CSKP_RAT (31-379): 1.01e-27: 123: 10.87		DLG1_RAT (30-615): 8.3e-64: 228: 13.60
+	Mm
		936188 DLG2_MOUSE (23-305): 9.03e-31: 132: 14.63		DLG3_MOUSE (109-615): 4.87e-59: 214: 13.10
+	Hs
		1077285 DLG2_HUMAN (23-305): 8.4e-31: 132: 15.33		DLG3_HUMAN (89-615): 5.93e-59: 213: 13.15
+	Mm
		1143467 DLG2_MOUSE (23-305): 9.03e-31: 132: 14.63		DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13
+	Hs
		942349 DLG2_HUMAN (23-305): 8.4e-31: 132: 15.33		DLG4_HUMAN (101-615): 8.81e-58: 208: 12.74
+	Mm
		936180 DLG3_MOUSE (27-533): 1.52e-26: 119: 14.34		DLG4_MOUSE (101-615): 1.09e-57: 208: 13.13