HitPredict

Interactor 1: DLG1 (P31007)
Disks large 1 tumor suppressor protein (Dlg)
Gene: DLG1

Interactor 2: Q9VBY7 (Q9VBY7)
Protein lin-7 homolog
Gene: veli

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.800

Property	Details
Experiments	23850283, 15039455
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, L27~L27_1, PDZ~PDZ
Common GO terms	GO:0016323 - basolateral plasma membrane GO:0045202 - synapse GO:0045211 - postsynaptic membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 970 Dm			1 195
+	Hs
		1021573 DLG1_HUMAN (1-970): 0: 634: 48.43		LIN7C_HUMAN (1-195): 2.28e-53: 170: 80.00
+	Mm
		292491 DLG1_MOUSE (1-970): 0: 634: 48.12		LIN7C_MOUSE (1-195): 2.28e-53: 170: 80.00
+	Hs
		1021563 DLG1_HUMAN (1-970): 0: 634: 48.43		LIN7B_HUMAN (1-195): 1.45e-52: 169: 77.44
+	Hs
		158277 DLG1_HUMAN (1-970): 0: 634: 48.43		LIN7A_HUMAN (6-194): 9.37e-50: 162: 77.78
+	Dm
		677679 DLG1_DROME (1-970): 0: 703: 100.00		DLG1_DROME (94-175): 2.48e-14: 72.4: 37.93
+	Mm
		1113136 Q3UP61_MOUSE (1-970): 0: 634: 48.66		DLG4_MOUSE (41-181): 1.8e-26: 107: 26.03
+	Mm
		1143387 DLG1_MOUSE (1-970): 0: 634: 48.12		DLG4_MOUSE (41-181): 1.8e-26: 107: 26.03
+	Hs
		1021482 DLG1_HUMAN (1-970): 0: 634: 48.43		DLG1_HUMAN (60-181): 5.33e-26: 106: 30.71
+	Rn
		677787 DLG1_RAT (1-970): 0: 632: 47.72		DLG4_RAT (41-181): 2.27e-26: 107: 26.03
+	Hs
		1021542 DLG1_HUMAN (1-970): 0: 634: 48.43		DLG3_HUMAN (79-164): 2.01e-19: 87.1: 35.17
+	Rn
		1144010 DLG1_RAT (1-970): 0: 632: 47.72		DLG3_RAT (60-164): 5.43e-20: 89: 30.00
+	Hs
		1021501 DLG1_HUMAN (1-970): 0: 634: 48.43		DLG2_HUMAN (4-85): 6.71e-10: 59.3: 9.64
+	Rn
		1144014 DLG1_RAT (1-970): 0: 632: 47.72		DLG2_RAT (4-85): 4.24e-10: 60.1: 8.43
+	Ce
		105542 DLG1_CAEEL (5-965): 6.08e-163: 505: 35.13		DLG1_CAEEL (58-177): 5.04e-20: 89: 24.80
+	Dm
		1181894 Q7KT16_DROME (393-965): 7.34e-110: 355: 23.15		Q9VBY7_DROME (1-195): 1.24e-52: 168: 100.00
+	Dm
		1362467 Q9VIJ4_DROME (497-922): 1.65e-37: 151: 29.82		Q9VBY7_DROME (1-195): 1.24e-52: 168: 100.00
+	Hs
		942349 DLG2_HUMAN (23-305): 8.4e-31: 132: 15.33		DLG4_HUMAN (41-181): 2.22e-26: 107: 26.03
+	Hs
		1077285 DLG2_HUMAN (23-305): 8.4e-31: 132: 15.33		DLG3_HUMAN (79-164): 2.01e-19: 87.1: 35.17